The Deming Luna Mimbres Museum was named for the City of Deming, Luna County, and the Mimbres Valley. It is housed in the old National Guard Armory which is located directly across the street from the Custom House and the Archives. Luna County Historical Society, a non-profit corporation, governs all three facilities.

1916	The building was built as a National Guard Armory and was used after Pancho Villa's raid on Columbus, New Mexico (30 miles south of Deming). It was the first Armory built after New Mexico became a state in 1912. In addition to military functions, the building was used for dances, basketball games, and a variety of social functions.
WWI	During WWI the building was used by the War Camp Community Service (forerunner of the USO).
WWII	During WWII, after the New Mexico National Guard was sent to phillpnines. The building was used as a USO to support soldiers training at Army and the Air Corp field in Deming. The building still bears the USO designation. After WWII it was again used as a Nat'l Guard Armory.
1972	The museum was started in a small cottage. It was started by volunteers and after 30 years and is till operated and supported by volunteers, visitors, citizens of the area, gifts, and endowments.
1977	The building was purchased from the State of New Mexico.
1977	The museum moved to the Armory building.
1978	The building was designated as a State Historic Site.
1980	An endowment fund was established by Pauline and Hubert Ruebush and, as a result, the museum has grown through the generosity of members and friends of the Luna County Historical Society.
1983	The building was placed on the National Register of Historic Places.

The museum continues to grow and since moving to this building, has had five major additions (art gallery, military room, ranching exhibit room, main street displays, and transportation room). In addition, the museum has acquired the Custom House and Archives which are located across the street.